What is Nano Fat Grafting?
Nano fat grafting is a form of autologous fat transfer. Fat is harvested from areas such as the abdomen or thighs using liposuction, then processed into a fine, emulsified form known as nano fat. This refined fat contains no intact fat cells, but is rich in regenerative components such as mesenchymal stem cells and growth factors.
Unlike traditional micro fat grafting, which restores volume in deeper facial compartments, nano fat is injected more superficially and is primarily used to improve skin texture, tone, and fine lines, rather than volume.
Clinical Benefits of Nano Fat Grafting
Nano fat grafting offers several advantages compared to synthetic fillers or other resurfacing techniques::
Natural and Biocompatible
Since the material is derived from the patient’s own fat, the risk of allergic reaction or rejection is eliminated.
Skin Rejuvenation
Nano fat contains regenerative cells that stimulate collagen production, leading to improved skin quality over time.
Long-Lasting Results
Although not permanent, results tend to last longer than those achieved with hyaluronic acid-based fillers, especially with proper skin care and follow-up.
Minimally Invasive
Performed under local or sedation anaesthesia, with minimal downtime and no need for general anaesthesia.

Common Treatment Areas
Nano fat grafting is commonly used to treat the following:
- Fine lines around the eyes and mouth
- Periorbital hollowing or dark under-eye circles
- Crepey skin on the cheeks or lower eyelids
- Skin laxity in the neck or décolletage
- Acne scars or irregular skin texture
It may also be combined with micro fat grafting for volume restoration, or surgical facelifts for comprehensive facial rejuvenation.
The Procedure at Ocean Clinic Marbella
At Ocean Clinic, nano fat grafting is carried out using a refined technique developed through years of clinical experience. The process includes:
- Harvesting – Fat is gently extracted via liposuction from a donor site (e.g., abdomen or inner thigh).
- Processing – The fat is mechanically filtered and emulsified to isolate the nano fat fraction.
- Injection – The nano fat is strategically injected into targeted areas using fine cannulas for precise placement.
The entire procedure typically takes between one and two hours and can be performed as a stand-alone treatment or in combination with other procedures.

Recovery and Results
Post-treatment downtime is minimal, with some swelling or bruising expected at both the donor and injection sites. Most patients resume normal activities within a few days.
Visible improvements in skin texture and tone become more noticeable within several weeks, with continued enhancement over the following months due to ongoing collagen stimulation.
Summary
Nano fat grafting represents a significant advancement in facial rejuvenation, offering a natural and regenerative alternative to synthetic fillers. Its ability to improve skin quality, reduce fine lines, and enhance facial harmony makes it a valuable tool in both aesthetic and restorative treatments.
To determine whether nano fat grafting is suitable for your goals, a personalised consultation at Ocean Clinic Marbella is recommended. The clinic’s multidisciplinary approach ensures each treatment plan is tailored to the individual’s needs, with the highest standards of safety and care.